Rounds

Overview

Each round begins with generating a large set of sequences, followed by selecting a library tailored to your experimental capacity. After testing these sequences and uploading the results, you can iterate through multiple rounds until your objectives are met.

What is a round?

One experimental round includes a full cycle of designing sequences, testing these in the lab and learning from the results of your assays.

Each round should have a specific strategy for sequence generation. You can create multiple parallel rounds for different hypotheses.

Rounds at Cradle

1

Create a round

You can create a round by clicking on the + New round button. You can give a round any name but use naming that makes it possible to distinguish rounds.

2

Configure sequence design

Configure the desired design of your sequences. Each round consists of one sequence generation. If you want to try different strategies, you can create multiple rounds.

Learn more here Sequence generation.

3

Download & review generated sequences

You download the sequences generated by Cradle and review the mutations.

4

Test in lab

You test your sequences in the lab to understand how close they come to your experimental goals.

5

Upload your lab results

To make sure that our models can learn and improve, you need to upload the results of your lab data.

By uploading the lab results, you train the model used to generate sequences for you. Based on this round's learnings, you set up a new round to further optimize your protein of interest.

Next steps

Once a round is created, you can begin configuring the Sequence generation for it.